Often the solution is to focus on what IS working.
For instance, one of the people in my online Writing Breakthrough Program said she's feeling blocked on her fiction project but is enjoying blogging.
My suggestion: create blogs written by the major characters about what they are going through. Obviously you don't have to make them public (but I'd keep them for possible "extras" later on).
It's a good way to get deep into your characters and understand how the story looks from their perspective.
Naturally at some point you will have to decide how to fit these multiple experiences together into your short story, novel, or script, but you will have plenty of material to work with and my bet is your block will be long gone.
(Want more practical help in writing your book or script? Get my latest book, Your Creative Writing Masterclass, to learn from the best writers of all time. You can order it from Amazon or your other favourite bookseller.)