The weakness of a lot of screenplays is that the protagonist's central problem isn't big enough. It has to be something formidable enough to keep them challenged for the entire script.
While many stories are about matters of life and death, the definition of "big" in this case is not objective but rather how important it is to the protagonist.
You can write a compelling screenplay featuring a character whose goal is objectively small, like winning a school race. The key is making sure it is of huge importance and consequence to the protagonist.
For instance, if the protagonist is a girl who is participating in a contest that is traditionally only for boys and if she's bullied, made fun of, and misunderstood even by the adults in her life we will feel the urgency of her quest and root for her to win.
IT HAS TO BE RELATABLE
The protagonist's challenge has to be relatable, but not necessarily in its specifics.
For instance, a protagonist may be striving to overcome a challenge with which we don't have any personal experience, but we can all relate to the feeling of having a big goal and having to fight for it.
When you are thinking about the central conflict of your protagonist, consider what makes it relatable for the audience. What is the emotion or goal that's driving the protagonist? For instance, it might be survival against a deadly force, the desire to better themselves, or righting a wrong.
THE PROTAGONIST HAS TO BE RELATABLE, TOO
Going back to the example of the school race, a big part of what makes us care in that example is the underdog nature of the girl. Most of us can relate to being misunderstood, to being made fun of, and to wanting to prove ourselves, just like her.
In many cases, the protagonist is likable from the start, but that's not essential. As long as they are interesting, we'll stick around, especially if we get the feeling that the story will give them a character arc that transforms them in a positive direction.
If the problem your protagonist faces seventy minutes in is the same level of difficulty as it was twenty minutes in there's a good chance we'll get bored before we get to minute seventy.
Just as a boxer has to fight opponents of increasing skill levels before taking on the champ, make your protagonist come up against bigger and bigger challenges. Let them have some small wins along the way, too, to keep them motivated, but each step of the way they should be in great danger of failing.
BE MEAN!
A writer I used to know never made it because he was too nice. Even in fiction, he couldn't bring himself to subject somebody to the kind of cruelty you'll have to impose upon your protagonist. In fact, he couldn't even imagine such cruelties in an original way, so his scripts were too derivative, relying on specific plot elements he'd seen in other films.
Don't be nice--this is one instance when any cruel impulses you may have can be put to good use!
ASK THESE QUESTIONS AT THE IDEA STAGE
It's unfortunate when a writer goes to all the effort of writing a complete screenplay before they discover that one of the above elements is missing.
Actually, often the person who discovers this first is an agent or producer for whom this lack is the reason they reject the script.
You can save yourself a lot of time by making sure at the idea stage that each of these is present. Ask yourself:
- Is the protagonist someone the audience will like or at least find interesting? What is it about them that the audience will find of interest or to which the audience can relate, like being an underdog or being confronted with unfair treatment?
- Is the challenge one the audience can relate to on a basic level? What is the protagonist's essential drive in facing this challenge, like righting a wrong, protecting their family, etc.?
- Does the conflict escalate as the story proceeds? What are the major steps of the conflict? (Tip: if you can put them in any different order without affecting the story, they're not escalating.)
If you have a strong answer to each of these questions, the odds are that your story will work.